Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22837.1TIGRFAM: AMMECR1; HAMAP: AMMECR1-domain protein; KEGG: sta:STHERM_c03350 hypothetical protein; PFAM: AMMECR1. (184 aa)    
Predicted Functional Partners:
AEH23172.1
PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; KEGG: dth:DICTH_1399 hypothetical protein; Belongs to the MEMO1 family.
    0.986
AEH22138.1
Radical SAM domain protein; KEGG: tye:THEYE_A0925 MoaA/NifB/PqqE family protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
     0.922
AEH22838.1
PFAM: Disulphide bond isomerase, DsbC/G, N-terminal; Glutaredoxin; KEGG: hth:HTH_1351 thiol:disulfide interchange protein.
       0.815
AEH22839.1
PFAM: Nitroreductase-like; KEGG: dak:DaAHT2_0557 nitroreductase.
 
    0.748
AEH22840.1
PFAM: NADPH-dependent FMN reductase; KEGG: iho:Igni_0620 NADPH-dependent FMN reductase.
  
    0.712
AEH23453.1
PFAM: Radical SAM; KEGG: mtp:Mthe_1490 radical SAM domain-containing protein.
 
     0.707
speE-2
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
       0.705
AEH23047.1
PFAM: UPF0103/Mediator of ErbB2-driven cell motility (Memo), related; KEGG: aae:aq_1336 hypothetical protein.
 
    0.566
AEH22842.1
KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal.
       0.513
nnrE
YjeF-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...]
   
  
 0.439
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.