Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
AEH22839.1PFAM: Nitroreductase-like; KEGG: dak:DaAHT2_0557 nitroreductase. (175 aa)    
Predicted Functional Partners:
AEH22840.1
PFAM: NADPH-dependent FMN reductase; KEGG: iho:Igni_0620 NADPH-dependent FMN reductase.
 
  
 0.848
speE-2
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
       0.815
AEH22837.1
TIGRFAM: AMMECR1; HAMAP: AMMECR1-domain protein; KEGG: sta:STHERM_c03350 hypothetical protein; PFAM: AMMECR1.
 
    0.748
AEH22838.1
PFAM: Disulphide bond isomerase, DsbC/G, N-terminal; Glutaredoxin; KEGG: hth:HTH_1351 thiol:disulfide interchange protein.
     
 0.718
AEH23593.1
YcaO-domain protein; TIGRFAM: YcaO-like; PFAM: YcaO-like; Tetratricopeptide TPR-1; KEGG: dol:Dole_1241 hypothetical protein; SMART: Tetratricopeptide repeat.
  
  
 0.655
AEH23601.1
KEGG: dak:DaAHT2_0589 protein of unknown function DUF181; TIGRFAM: YcaO-like; PFAM: YcaO-like.
  
  
 0.590
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.578
AEH22544.1
PFAM: ABC-2 type transporter; KEGG: tye:THEYE_A1624 ATPase component ABC-type multidrug transport system.
  
    0.567
AEH22545.1
PFAM: ABC-2 type transporter; KEGG: tye:THEYE_A1623 ABC-2 type transporter.
  
    0.567
AEH22836.1
PFAM: ABC-2 type transporter; KEGG: tye:THEYE_A1645 ABC-2 type transporter superfamily.
  
    0.567
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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