Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22840.1PFAM: NADPH-dependent FMN reductase; KEGG: iho:Igni_0620 NADPH-dependent FMN reductase. (239 aa)    
Predicted Functional Partners:
AEH22839.1
PFAM: Nitroreductase-like; KEGG: dak:DaAHT2_0557 nitroreductase.
 
  
 0.848
speE-2
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine; Belongs to the spermidine/spermine synthase family.
       0.815
AEH22837.1
TIGRFAM: AMMECR1; HAMAP: AMMECR1-domain protein; KEGG: sta:STHERM_c03350 hypothetical protein; PFAM: AMMECR1.
  
    0.712
AEH22838.1
PFAM: Disulphide bond isomerase, DsbC/G, N-terminal; Glutaredoxin; KEGG: hth:HTH_1351 thiol:disulfide interchange protein.
       0.705
AEH22586.1
TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; Trehalose-phosphatase; KEGG: hth:HTH_0762 trehalose-6-phosphate synthase; PFAM: Glycosyl transferase, family 20; Trehalose-phosphatase.
   
    0.632
AEH22842.1
KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal.
  
    0.592
AEH22703.1
KEGG: dsa:Desal_3394 hypothetical protein.
 
     0.451
AEH22843.1
PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding.
       0.424
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
       0.424
AEH22947.1
Hypothetical protein; KEGG: sat:SYN_01357 putative cytoplasmic protein.
  
     0.402
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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