| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22433.1 | AEH22762.1 | TOPB45_0321 | TOPB45_0660 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | UDP-glucuronate 5'-epimerase; KEGG: pmx:PERMA_0403 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase. | 0.536 |
| AEH22433.1 | AEH22845.1 | TOPB45_0321 | TOPB45_0744 | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | 0.492 |
| AEH22762.1 | AEH22433.1 | TOPB45_0660 | TOPB45_0321 | UDP-glucuronate 5'-epimerase; KEGG: pmx:PERMA_0403 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase. | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.536 |
| AEH22762.1 | AEH22845.1 | TOPB45_0660 | TOPB45_0744 | UDP-glucuronate 5'-epimerase; KEGG: pmx:PERMA_0403 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase. | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | 0.621 |
| AEH22842.1 | AEH22843.1 | TOPB45_0741 | TOPB45_0742 | KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal. | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | 0.573 |
| AEH22842.1 | AEH22845.1 | TOPB45_0741 | TOPB45_0744 | KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal. | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | 0.508 |
| AEH22842.1 | glyA | TOPB45_0741 | TOPB45_0743 | KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.575 |
| AEH22843.1 | AEH22842.1 | TOPB45_0742 | TOPB45_0741 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal. | 0.573 |
| AEH22843.1 | AEH22845.1 | TOPB45_0742 | TOPB45_0744 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | 0.637 |
| AEH22843.1 | AEH22846.1 | TOPB45_0742 | TOPB45_0745 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | KEGG: hya:HY04AAS1_0581 hypothetical protein. | 0.445 |
| AEH22843.1 | glyA | TOPB45_0742 | TOPB45_0743 | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.828 |
| AEH22845.1 | AEH22433.1 | TOPB45_0744 | TOPB45_0321 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | TIGRFAM: Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: dte:Dester_1366 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Mannose-6-phosphate isomerase, type II, C-terminal; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family. | 0.492 |
| AEH22845.1 | AEH22762.1 | TOPB45_0744 | TOPB45_0660 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | UDP-glucuronate 5'-epimerase; KEGG: pmx:PERMA_0403 NAD-dependent epimerase/dehydratase family protein; PFAM: NAD-dependent epimerase/dehydratase. | 0.621 |
| AEH22845.1 | AEH22842.1 | TOPB45_0744 | TOPB45_0741 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | KEGG: dak:DaAHT2_1329 chaperone DnaJ domain protein; PFAM: Heat shock protein DnaJ, N-terminal; Chaperone DnaJ, C-terminal; SMART: Heat shock protein DnaJ, N-terminal. | 0.508 |
| AEH22845.1 | AEH22843.1 | TOPB45_0744 | TOPB45_0742 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | 0.637 |
| AEH22845.1 | AEH22846.1 | TOPB45_0744 | TOPB45_0745 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | KEGG: hya:HY04AAS1_0581 hypothetical protein. | 0.530 |
| AEH22845.1 | AEH22891.1 | TOPB45_0744 | TOPB45_0790 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | PFAM: Glycosyl transferase, family 39; KEGG: hth:HTH_0673 glycosyltransferase, family 39. | 0.498 |
| AEH22845.1 | AEH23071.1 | TOPB45_0744 | TOPB45_0976 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | Hypothetical protein; KEGG: pfo:Pfl01_2836 glycosyl transferase family protein. | 0.457 |
| AEH22845.1 | glyA | TOPB45_0744 | TOPB45_0743 | PFAM: Glycosyl transferase, family 2; KEGG: saf:SULAZ_0943 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase (undecaprenyl-phosphate Ara4FN transferase) (Ara4FN transferase). | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.636 |
| AEH22846.1 | AEH22843.1 | TOPB45_0745 | TOPB45_0742 | KEGG: hya:HY04AAS1_0581 hypothetical protein. | PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: ter:Tery_2084 CMP/dCMP deaminase, zinc-binding. | 0.445 |