Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22935.1KEGG: ddf:DEFDS_1930 phosphatase Ppx/GppA family; PFAM: Ppx/GppA phosphatase; Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein. (402 aa)    
Predicted Functional Partners:
AEH23494.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
 
 0.957
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.847
AEH22934.1
KEGG: gur:Gura_2285 signal peptide peptidase SppA, 36K type; TIGRFAM: Peptidase S49, SppA; PFAM: Peptidase S49.
  
    0.826
AEH22933.1
PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tth:TTC1824 30S ribosomal protein S1.
  
  
 0.810
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.786
AEH22937.1
PFAM: Type II secretion system F domain; KEGG: gbm:Gbem_2593 type IV pilus biogenesis protein PilC.
       0.732
AEH22938.1
PFAM: Mg2+ transporter protein, CorA-like; KEGG: afl:Aflv_1374 metal ion transporter.
       0.701
AEH22932.1
PFAM: Polynucleotide adenylyltransferase region; KEGG: dtu:Dtur_1497 CBS domain containing protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
     
 0.693
AEH22925.1
Agmatinase; TIGRFAM: Putative agmatinase; KEGG: dth:DICTH_1308 agmatinase, putative; PFAM: Ureohydrolase; Belongs to the arginase family.
     
 0.688
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
       0.673
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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