| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22940.1 | AEH22943.1 | TOPB45_0842 | TOPB45_0845 | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | 0.797 |
| AEH22940.1 | murA | TOPB45_0842 | TOPB45_0844 | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.811 |
| AEH22940.1 | prmC | TOPB45_0842 | TOPB45_0843 | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.813 |
| AEH22940.1 | uppP | TOPB45_0842 | TOPB45_0841 | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.811 |
| AEH22943.1 | AEH22940.1 | TOPB45_0845 | TOPB45_0842 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | 0.797 |
| AEH22943.1 | murA | TOPB45_0845 | TOPB45_0844 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.816 |
| AEH22943.1 | prmC | TOPB45_0845 | TOPB45_0843 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.846 |
| AEH22943.1 | uppP | TOPB45_0845 | TOPB45_0841 | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.783 |
| lpxA | murA | TOPB45_0030 | TOPB45_0844 | Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.880 |
| murA | AEH22940.1 | TOPB45_0844 | TOPB45_0842 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | PFAM: Methyltransferase-16, putative; KEGG: dpr:Despr_2610 methyltransferase-16, putative. | 0.811 |
| murA | AEH22943.1 | TOPB45_0844 | TOPB45_0845 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: aar:Acear_0044 DNA polymerase III subunit delta'. | 0.816 |
| murA | lpxA | TOPB45_0844 | TOPB45_0030 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.880 |
| murA | murB | TOPB45_0844 | TOPB45_0945 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.978 |
| murA | murD | TOPB45_0844 | TOPB45_0942 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.836 |
| murA | murE | TOPB45_0844 | TOPB45_0939 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.819 |
| murA | murF | TOPB45_0844 | TOPB45_0940 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.835 |
| murA | murG | TOPB45_0844 | TOPB45_0943 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.840 |
| murA | prmC | TOPB45_0844 | TOPB45_0843 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.818 |
| murA | uppP | TOPB45_0844 | TOPB45_0841 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. | 0.875 |
| murB | murA | TOPB45_0945 | TOPB45_0844 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.978 |