| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22140.1 | AEH23691.1 | TOPB45_0023 | TOPB45_1613 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: sat:SYN_00123 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. | TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. | 0.900 |
| AEH22140.1 | apgM | TOPB45_0023 | TOPB45_0850 | TIGRFAM: D-3-phosphoglycerate dehydrogenase; KEGG: sat:SYN_00123 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Amino acid-binding ACT. | Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.900 |
| AEH22408.1 | AEH22985.1 | TOPB45_0294 | TOPB45_0887 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | 0.800 |
| AEH22408.1 | AEH23481.1 | TOPB45_0294 | TOPB45_1400 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.983 |
| AEH22408.1 | AEH23691.1 | TOPB45_0294 | TOPB45_1613 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. | 0.815 |
| AEH22408.1 | apgM | TOPB45_0294 | TOPB45_0850 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.815 |
| AEH22408.1 | eno | TOPB45_0294 | TOPB45_0128 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.981 |
| AEH22408.1 | fbp | TOPB45_0294 | TOPB45_0677 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.927 |
| AEH22408.1 | pgk | TOPB45_0294 | TOPB45_0105 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.940 |
| AEH22408.1 | rnhA | TOPB45_0294 | TOPB45_1464 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Ribonuclease H; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.800 |
| AEH22408.1 | tal | TOPB45_0294 | TOPB45_0487 | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.970 |
| AEH22985.1 | AEH22408.1 | TOPB45_0887 | TOPB45_0294 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 0.800 |
| AEH22985.1 | AEH23481.1 | TOPB45_0887 | TOPB45_1400 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | 0.800 |
| AEH22985.1 | AEH23691.1 | TOPB45_0887 | TOPB45_1613 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | TIGRFAM: Homoserine kinase, putative; Cofactor-independent phosphoglycerate mutase, archaeal; KEGG: tye:THEYE_A1682 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Metalloenzyme. | 0.900 |
| AEH22985.1 | apgM | TOPB45_0887 | TOPB45_0850 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | Phosphonopyruvate decarboxylase-related protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. | 0.912 |
| AEH22985.1 | fbp | TOPB45_0887 | TOPB45_0677 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | Protein of unknown function DUF100; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P). | 0.900 |
| AEH22985.1 | pgk | TOPB45_0887 | TOPB45_0105 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | HAMAP: Phosphoglycerate kinase; KEGG: ddf:DEFDS_1892 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. | 0.915 |
| AEH22985.1 | rnhA | TOPB45_0887 | TOPB45_1464 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | Ribonuclease H; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. | 0.800 |
| AEH22985.1 | tal | TOPB45_0887 | TOPB45_0487 | KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.800 |
| AEH23481.1 | AEH22408.1 | TOPB45_1400 | TOPB45_0294 | 1-deoxy-D-xylulose-5-phosphate synthase; KEGG: sfu:Sfum_1302 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal. | PFAM: Phosphoglucose isomerase (PGI); KEGG: sfu:Sfum_1952 phosphoglucose isomerase; Belongs to the GPI family. | 0.983 |