Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22973.1PFAM: Deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; KEGG: aae:aq_257 RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (432 aa)    
Predicted Functional Partners:
AEH22974.1
CoA-substrate-specific enzyme activase; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase.
       0.594
AEH23519.1
protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
   
  
 0.589
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.466
pheT
TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; KEGG: chy:CHY_1570 phenylalanyl-tRNA synthetase subunit beta.
 
  
 0.447
AEH22933.1
PFAM: Ribosomal protein S1, RNA binding domain; KEGG: tth:TTC1824 30S ribosomal protein S1.
   
    0.408
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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