Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22974.1CoA-substrate-specific enzyme activase; KEGG: tye:THEYE_A0388 (R)-2-hydroxyglutaryl-CoA dehydratase activator-related protein; TIGRFAM: CoA enzyme activase; PFAM: ATPase, BadF/BadG/BcrA/BcrD type; Protein of unknown function DUF2229, CoA enzyme activase. (1395 aa)    
Predicted Functional Partners:
AEH23525.1
PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; KEGG: tye:THEYE_A1140 2-hydroxyglutaryl-CoA dehydratase, beta subunit-like protein.
  
 
 0.821
AEH22975.1
KEGG: tye:THEYE_A0149 hypothetical protein.
       0.627
AEH22976.1
Hypothetical protein.
       0.614
atpB
ATP synthase subunit a; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
       0.606
AEH22973.1
PFAM: Deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; KEGG: aae:aq_257 RNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
       0.594
atpE
ATP synthase subunit c; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
       0.499
AEH22980.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: atm:ANT_09900 putative phosphatidylinositol synthase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.418
AEH23277.1
KEGG: tye:THEYE_A0253 hypothetical protein.
  
     0.416
queH
Protein of unknown function DUF208; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).
 
     0.412
AEH22340.1
PFAM: Transcriptional regulator, TetR-like, DNA-binding, bacterial/archaeal; KEGG: tye:THEYE_A0116 transcriptional regulator, TetR family.
 
   
 0.407
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.