Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH22984.1TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence; KEGG: dte:Dester_0453 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit. (305 aa)    
Predicted Functional Partners:
AEH22983.1
KEGG: dte:Dester_0454 cytochrome-c3 hydrogenase; PFAM: Nickel-dependent hydrogenase, large subunit.
 
 
 0.997
AEH22569.1
Hydrogenase expression/formation protein; KEGG: aae:aq_667 HupD hydrogenase related function; TIGRFAM: Peptidase A31, hydrogenase expression/formation protein; Peptidase A31, hydrogen uptake protein; PFAM: Peptidase A31, hydrogen uptake protein.
 
  
 0.868
AEH23291.1
PFAM: Polysulphide reductase, NrfD; KEGG: sfu:Sfum_1150 polysulfide reductase, NrfD.
  
  
 0.591
AEH23567.1
PFAM: Polysulphide reductase, NrfD; KEGG: tye:THEYE_A1280 polysulphide reductase, NrfD superfamily.
  
  
 0.591
hypA
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
  
 0.532
AEH22982.1
KEGG: hth:HTH_1814 hydrogenase expression/formation protein; TIGRFAM: Hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein.
 
  
 0.482
AEH22567.1
KEGG: hth:HTH_1006 hydrogenase expression/formation protein; TIGRFAM: Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein.
 
   
 0.481
AEH22985.1
KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal.
       0.470
AEH22566.1
KEGG: saf:SULAZ_0746 hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like.
  
  
 0.464
AEH22522.1
Acylphosphatase; TIGRFAM: Hydrogenase maturation factor, HypF-type; HAMAP: Acylphosphatase; KEGG: tte:TTE0131 hydrogenase maturation factor; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type.
   
 
 0.426
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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