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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH22987.1PFAM: Protein of unknown function DUF318, transmembrane; KEGG: afu:AF2247 hypothetical protein. (351 aa)    
Predicted Functional Partners:
AEH22988.1
TIGRFAM: Redox-active disulphide protein 2; KEGG: apo:Arcpr_0666 redox-active disulfide protein 2.
 
  
 0.936
AEH22986.1
Regulatory protein ArsR; KEGG: tye:THEYE_A0200 heavy metal resistance transcription regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
 
  
 0.858
AEH22989.1
PFAM: Formylmethanofuran dehydrogenase, subunit E region; KEGG: sun:SUN_1417 hypothetical protein.
 
    0.683
AEH22990.1
PFAM: Protein of unknown function DUF81; KEGG: rrs:RoseRS_2089 hypothetical protein.
       0.546
AEH22985.1
KEGG: iag:Igag_1482 aldehyde ferredoxin oxidoreductase; PFAM: Aldehyde ferredoxin oxidoreductase, N-terminal; Aldehyde ferredoxin oxidoreductase, C-terminal; SMART: Aldehyde ferredoxin oxidoreductase, N-terminal.
       0.500
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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