Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22988.1TIGRFAM: Redox-active disulphide protein 2; KEGG: apo:Arcpr_0666 redox-active disulfide protein 2. (80 aa)    
Predicted Functional Partners:
AEH22987.1
PFAM: Protein of unknown function DUF318, transmembrane; KEGG: afu:AF2247 hypothetical protein.
 
  
 0.931
AEH22658.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.850
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.782
AEH22989.1
PFAM: Formylmethanofuran dehydrogenase, subunit E region; KEGG: sun:SUN_1417 hypothetical protein.
 
     0.744
AEH22986.1
Regulatory protein ArsR; KEGG: tye:THEYE_A0200 heavy metal resistance transcription regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR.
     
 0.707
AEH22990.1
PFAM: Protein of unknown function DUF81; KEGG: rrs:RoseRS_2089 hypothetical protein.
       0.661
AEH22615.1
Hypothetical protein.
    
 0.653
murE
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
    
   0.587
AEH22483.1
CoA-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: dps:DP2890 NADH oxidase; SMART: Rhodanese-like.
   
 
 0.570
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
    
  0.567
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.