Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH22999.1PFAM: Protein of unknown function DUF81; KEGG: tye:THEYE_A1129 hypothetical protein. (134 aa)    
Predicted Functional Partners:
AEH22998.1
PFAM: Protein of unknown function DUF81; KEGG: tye:THEYE_A1130 hypothetical protein.
 
     0.944
AEH22995.1
Nitrate reductase; KEGG: tye:THEYE_A1128 thiosulfate reductase; PFAM: Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 region; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
     0.643
AEH23326.1
KEGG: tye:THEYE_A0760 hypothetical protein.
  
     0.607
AEH23425.1
PFAM: Methyltransferase type 12; KEGG: tye:THEYE_A2047 hypothetical protein.
  
     0.570
AEH22572.1
KEGG: tye:THEYE_A0737 hypothetical protein.
 
    0.517
AEH23325.1
PFAM: Protein of unknown function DUF81; KEGG: tye:THEYE_A0761 hypothetical protein.
  
     0.493
AEH23382.1
KEGG: tye:THEYE_A0864 hypothetical protein.
  
     0.490
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
       0.464
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
       0.464
AEH23002.1
KEGG: dak:DaAHT2_1547 hypothetical protein.
       0.464
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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