| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22159.1 | AEH23127.1 | TOPB45_0042 | TOPB45_1033 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | 0.416 |
| AEH22159.1 | AEH23436.1 | TOPB45_0042 | TOPB45_1355 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | 0.440 |
| AEH22159.1 | AEH23574.1 | TOPB45_0042 | TOPB45_1496 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | 0.924 |
| AEH22159.1 | mutL | TOPB45_0042 | TOPB45_0218 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.418 |
| AEH22159.1 | polA | TOPB45_0042 | TOPB45_0793 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.531 |
| AEH22159.1 | uvrB | TOPB45_0042 | TOPB45_0309 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.989 |
| AEH22159.1 | uvrC | TOPB45_0042 | TOPB45_0907 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.804 |
| AEH22186.1 | polA | TOPB45_0070 | TOPB45_0793 | TIGRFAM: DNA glycosylase/AP lyase; KEGG: adg:Adeg_1023 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.979 |
| AEH22186.1 | uvrC | TOPB45_0070 | TOPB45_0907 | TIGRFAM: DNA glycosylase/AP lyase; KEGG: adg:Adeg_1023 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.672 |
| AEH23003.1 | AEH23005.1 | TOPB45_0906 | TOPB45_0908 | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | 0.512 |
| AEH23003.1 | polA | TOPB45_0906 | TOPB45_0793 | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.543 |
| AEH23003.1 | uvrC | TOPB45_0906 | TOPB45_0907 | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.798 |
| AEH23005.1 | AEH23003.1 | TOPB45_0908 | TOPB45_0906 | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | 0.512 |
| AEH23005.1 | uvrC | TOPB45_0908 | TOPB45_0907 | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.602 |
| AEH23127.1 | AEH22159.1 | TOPB45_1033 | TOPB45_0042 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.416 |
| AEH23127.1 | AEH23436.1 | TOPB45_1033 | TOPB45_1355 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | 0.928 |
| AEH23127.1 | AEH23574.1 | TOPB45_1033 | TOPB45_1496 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | 0.437 |
| AEH23127.1 | mutL | TOPB45_1033 | TOPB45_0218 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | DNA mismatch repair protein mutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.666 |
| AEH23127.1 | polA | TOPB45_1033 | TOPB45_0793 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.686 |
| AEH23127.1 | uvrB | TOPB45_1033 | TOPB45_0309 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.726 |
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