| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22159.1 | AEH23574.1 | TOPB45_0042 | TOPB45_1496 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | 0.924 |
| AEH22159.1 | ruvA | TOPB45_0042 | TOPB45_0576 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.434 |
| AEH22159.1 | ruvB | TOPB45_0042 | TOPB45_0549 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.503 |
| AEH22159.1 | uvrB | TOPB45_0042 | TOPB45_0309 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.987 |
| AEH22159.1 | uvrC | TOPB45_0042 | TOPB45_0907 | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.796 |
| AEH22186.1 | ruvA | TOPB45_0070 | TOPB45_0576 | TIGRFAM: DNA glycosylase/AP lyase; KEGG: adg:Adeg_1023 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding. | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.414 |
| AEH22186.1 | uvrC | TOPB45_0070 | TOPB45_0907 | TIGRFAM: DNA glycosylase/AP lyase; KEGG: adg:Adeg_1023 formamidopyrimidine-DNA glycosylase; PFAM: DNA glycosylase/AP lyase, catalytic domain; DNA glycosylase/AP lyase, H2TH DNA-binding. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.687 |
| AEH23003.1 | uvrC | TOPB45_0906 | TOPB45_0907 | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.800 |
| AEH23127.1 | AEH23436.1 | TOPB45_1033 | TOPB45_1355 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | 0.928 |
| AEH23127.1 | radA | TOPB45_1033 | TOPB45_0490 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.597 |
| AEH23127.1 | uvrC | TOPB45_1033 | TOPB45_0907 | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.639 |
| AEH23436.1 | AEH23127.1 | TOPB45_1355 | TOPB45_1033 | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | 0.928 |
| AEH23436.1 | radA | TOPB45_1355 | TOPB45_0490 | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.597 |
| AEH23436.1 | uvrC | TOPB45_1355 | TOPB45_0907 | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.637 |
| AEH23574.1 | AEH22159.1 | TOPB45_1496 | TOPB45_0042 | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.924 |
| AEH23574.1 | ruvB | TOPB45_1496 | TOPB45_0549 | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.416 |
| AEH23574.1 | uvrB | TOPB45_1496 | TOPB45_0309 | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] | 0.985 |
| AEH23574.1 | uvrC | TOPB45_1496 | TOPB45_0907 | PFAM: ABC transporter-like; KEGG: tye:THEYE_A1038 excinuclease ABC, A subunit. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.803 |
| radA | AEH23127.1 | TOPB45_0490 | TOPB45_1033 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | PFAM: DNA helicase, UvrD/REP type; KEGG: tye:THEYE_A0217 ATP-dependent DNA helicase PcrA. | 0.597 |
| radA | AEH23436.1 | TOPB45_0490 | TOPB45_1355 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | PFAM: DNA helicase, UvrD/REP type; KEGG: rmr:Rmar_0453 UvrD/REP helicase. | 0.597 |
