| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22354.1 | AEH22563.1 | TOPB45_0240 | TOPB45_0460 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | 0.903 |
| AEH22354.1 | AEH23005.1 | TOPB45_0240 | TOPB45_0908 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | 0.509 |
| AEH22354.1 | AEH23174.1 | TOPB45_0240 | TOPB45_1083 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: nis:NIS_0684 signal transduction response regulator; SMART: Diguanylate cyclase, predicted. | 0.763 |
| AEH22354.1 | AEH23282.1 | TOPB45_0240 | TOPB45_1195 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | 0.755 |
| AEH22354.1 | AEH23548.1 | TOPB45_0240 | TOPB45_1469 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | KEGG: dpr:Despr_1818 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction response regulator, receiver region. | 0.790 |
| AEH22354.1 | AEH23656.1 | TOPB45_0240 | TOPB45_1578 | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; KEGG: atu:Atu1362 two component sensor kinase; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction response regulator, receiver region. | 0.702 |
| AEH22421.1 | AEH22563.1 | TOPB45_0308 | TOPB45_0460 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | 0.430 |
| AEH22421.1 | AEH23005.1 | TOPB45_0308 | TOPB45_0908 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | 0.521 |
| AEH22421.1 | AEH23656.1 | TOPB45_0308 | TOPB45_1578 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; KEGG: atu:Atu1362 two component sensor kinase; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction response regulator, receiver region. | 0.411 |
| AEH22563.1 | AEH22354.1 | TOPB45_0460 | TOPB45_0240 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | TIGRFAM: Diguanylate cyclase, predicted; Haemerythrin-like, metal-binding; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: pmx:PERMA_0255 diguanylate cyclase/phosphodiesterase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted. | 0.903 |
| AEH22563.1 | AEH22421.1 | TOPB45_0460 | TOPB45_0308 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.430 |
| AEH22563.1 | AEH23005.1 | TOPB45_0460 | TOPB45_0908 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | 0.597 |
| AEH22563.1 | AEH23174.1 | TOPB45_0460 | TOPB45_1083 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: nis:NIS_0684 signal transduction response regulator; SMART: Diguanylate cyclase, predicted. | 0.893 |
| AEH22563.1 | AEH23282.1 | TOPB45_0460 | TOPB45_1195 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | 0.885 |
| AEH22563.1 | AEH23548.1 | TOPB45_0460 | TOPB45_1469 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | KEGG: dpr:Despr_1818 CheA signal transduction histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup, homodimeric; Signal transduction histidine kinase, phosphotransfer (Hpt) region; CheW-like protein; SMART: CheW-like protein; ATP-binding region, ATPase-like; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction response regulator, receiver region. | 0.950 |
| AEH22563.1 | AEH23656.1 | TOPB45_0460 | TOPB45_1578 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; KEGG: atu:Atu1362 two component sensor kinase; SMART: ATP-binding region, ATPase-like; PAS; Signal transduction response regulator, receiver region. | 0.989 |
| AEH22563.1 | uvrC | TOPB45_0460 | TOPB45_0907 | Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; KEGG: saf:SULAZ_0401 PAS fold family protein; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS. | UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.441 |
| AEH22759.1 | AEH23003.1 | TOPB45_0657 | TOPB45_0906 | KEGG: pas:Pars_0947 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; Major facilitator superfamily MFS-1; SMART: Cystathionine beta-synthase, core. | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | 0.401 |
| AEH22759.1 | AEH23005.1 | TOPB45_0657 | TOPB45_0908 | KEGG: pas:Pars_0947 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; Major facilitator superfamily MFS-1; SMART: Cystathionine beta-synthase, core. | KEGG: geo:Geob_2600 transcriptional regulator, LuxR family; PFAM: Transcription regulator LuxR, C-terminal; SMART: Transcription regulator LuxR, C-terminal. | 0.496 |
| AEH23003.1 | AEH22759.1 | TOPB45_0906 | TOPB45_0657 | KEGG: tye:THEYE_A0114 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase. | KEGG: pas:Pars_0947 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; Major facilitator superfamily MFS-1; SMART: Cystathionine beta-synthase, core. | 0.401 |