Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH23072.1Y414 protein; KEGG: aae:aq_1106 hypothetical protein; TIGRFAM: Y414; PFAM: ATP dependent DNA ligase, central. (384 aa)    
Predicted Functional Partners:
AEH23511.1
UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
 
     0.786
AEH23073.1
TIGRFAM: Sirohaem synthase, N-terminal; KEGG: adg:Adeg_1261 siroheme synthase.
       0.779
AEH23046.1
KEGG: aae:aq_324 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease.
  
     0.745
rtcA
RNA 3'-phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
     0.707
AEH23071.1
Hypothetical protein; KEGG: pfo:Pfl01_2836 glycosyl transferase family protein.
 
     0.696
AEH23387.1
KEGG: pca:Pcar_3121 hypothetical protein.
  
     0.665
AEH22784.1
PFAM: Rickettsia 17kDa surface antigen; KEGG: tal:Thal_0566 17 kDa surface antigen.
  
     0.634
AEH23069.1
PFAM: Creatininase; KEGG: sfu:Sfum_0661 creatininase.
       0.606
AEH23134.1
TIGRFAM: putative regulatory domain-containing; KEGG: saf:SULAZ_0617 hypothetical protein.
  
     0.602
AEH23106.1
PFAM: Protein of unknown function DUF6, transmembrane; KEGG: toc:Toce_2211 protein of unknown function DUF6 transmembrane.
  
     0.597
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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