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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH23106.1PFAM: Protein of unknown function DUF6, transmembrane; KEGG: toc:Toce_2211 protein of unknown function DUF6 transmembrane. (141 aa)    
Predicted Functional Partners:
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.723
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
       0.723
AEH23107.1
PFAM: Peptidase M50; KEGG: dps:DP0062 hypothetical protein.
       0.610
AEH23108.1
TIGRFAM: Peptidase S41A, C-terminal protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; KEGG: sfu:Sfum_3063 carboxyl-terminal protease; SMART: Peptidase S41; PDZ/DHR/GLGF; Belongs to the peptidase S41A family.
       0.610
AEH23072.1
Y414 protein; KEGG: aae:aq_1106 hypothetical protein; TIGRFAM: Y414; PFAM: ATP dependent DNA ligase, central.
  
     0.597
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.595
AEH23046.1
KEGG: aae:aq_324 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease.
  
     0.560
AEH23511.1
UPF0278 protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family.
  
     0.548
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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