Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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AEH23135.1Putative circadian clock protein, KaiC; KEGG: saf:SULAZ_0618 ATPase, RecA-superfamily; TIGRFAM: KaiC domain protein, AF_0795 family; PFAM: Circadian clock protein KaiC, central region. (302 aa)    
Predicted Functional Partners:
AEH23134.1
TIGRFAM: putative regulatory domain-containing; KEGG: saf:SULAZ_0617 hypothetical protein.
 
     0.949
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
 
     0.745
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.685
AEH23046.1
KEGG: aae:aq_324 hypothetical protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease.
  
     0.655
AEH23137.1
PFAM: DNA polymerase III, delta; KEGG: ssp:SSP1171 DNA polymerase III subunit delta.
 
     0.577
AEH22407.1
PFAM: Membrane protein, aromatic hydrocarbon degradation; KEGG: hth:HTH_1772 long-chain fatty acid transport protein.
  
     0.541
AEH23136.1
TIGRFAM: Pyruvate kinase; KEGG: pmx:PERMA_0022 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; Belongs to the pyruvate kinase family.
       0.532
AEH22742.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: hth:HTH_1631 CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
     0.519
smc
SMC domain protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
       0.496
AEH22438.1
Virulence factor MVIN family protein; PFAM: Flagellin assembly, membrane protein MviN; KEGG: aae:aq_509 hypothetical protein.
  
     0.494
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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