Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
AEH23180.1AAA ATPase central domain protein; KEGG: msk:Msui08060 cell division protease FtsH-like protein; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core. (422 aa)    
Predicted Functional Partners:
AEH22541.1
PFAM: Histone deacetylase superfamily; KEGG: sat:SYN_00740 histone deacetylase family protein.
    
 0.836
dnaK
Chaperone protein dnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.778
AEH23181.1
Hypothetical protein.
       0.773
AEH22615.1
Hypothetical protein.
    
 0.767
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 
 0.643
AEH23254.1
Xenobiotic-transporting ATPase; PFAM: ABC transporter-like; ABC transporter, transmembrane region; KEGG: ddf:DEFDS_0328 ABC transporter ATP-binding protein; SMART: ATPase, AAA+ type, core.
 
 
 0.631
AEH23143.1
KEGG: rrs:RoseRS_0892 WD-40 repeat-containing protein; PFAM: WD40 repeat, subgroup; SMART: WD40 repeat.
   
 
 0.556
AEH22906.1
KEGG: sul:SYO3AOP1_1425 hypothetical protein.
    
 
 0.547
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
   0.492
AEH23028.1
Fe(3+)-transporting ATPase; PFAM: ABC transporter-like; KEGG: mka:MK1523 ABC-type molibdate transport systems, ATPase component; SMART: ATPase, AAA+ type, core.
  
     0.486
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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