Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH23212.1PFAM: K+ potassium transporter; KEGG: tye:THEYE_A1816 potassium uptake protein Kup. (597 aa)    
Predicted Functional Partners:
AEH23213.1
TIGRFAM: Diguanylate cyclase, predicted; PFAM: Diguanylate cyclase, predicted; CHASE4; KEGG: cbo:CBO0357 signaling protein; SMART: Diguanylate cyclase, predicted.
       0.574
AEH22355.1
PFAM: Cation/H+ exchanger; Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: tye:THEYE_A1050 sodium/hydrogen exchanger family/TrkA domain protein; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.457
AEH23336.1
KEGG: hth:HTH_0871 ferredoxin-dependent glutamate synthase; PFAM: Glutamate synthase, central-C; Glutamine amidotransferase, class-II; Glutamate synthase, central-N; Glutamate synthase, alpha subunit, C-terminal.
      
 0.419
AEH23214.1
PFAM: Peptidase M54, archaemetzincin; KEGG: tye:THEYE_A0526 hypothetical protein.
       0.415
AEH22759.1
KEGG: pas:Pars_0947 CBS domain-containing protein; PFAM: Cystathionine beta-synthase, core; Major facilitator superfamily MFS-1; SMART: Cystathionine beta-synthase, core.
  
   
 0.406
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.