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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (324 aa)    
Predicted Functional Partners:
cas2-2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.987
AEH23310.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 
 0.981
AEH23309.1
TIGRFAM: Helicase Cas3, CRISPR-associated, core; CRISPR-associated HD domain; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; KEGG: cow:Calow_0071 crispr-associated helicase cas3; SMART: DNA/RNA helicase, C-terminal; DEAD-like helicase, N-terminal.
 
  
 0.954
AEH23308.1
TIGRFAM: CRISPR-associated protein Cas5, Tneap type; CRISPR-associated protein Cas5; KEGG: cow:Calow_0070 crispr-associated protein cas5 family.
 
   
 0.945
cas2
CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
  
 
 0.777
AEH23307.1
KEGG: tal:Thal_0005 CRISPR-associated protein Cas6; TIGRFAM: CRISPR-associated protein, Cas6; PFAM: Protein of unknown function DUF57.
 
   
 0.754
AEH23197.1
TIGRFAM: CRISPR-associated protein Csm1; KEGG: saf:SULAZ_1602 crispr-associated protein, Csm1 family.
 
  
 0.604
AEH23199.1
KEGG: saf:SULAZ_1604 crispr-associated RAMP protein, Csm3 family; TIGRFAM: CRISPR-associated RAMP Csm3; PFAM: Protein of unknown function DUF324.
 
     0.571
AEH22935.1
KEGG: ddf:DEFDS_1930 phosphatase Ppx/GppA family; PFAM: Ppx/GppA phosphatase; Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein.
    
   0.422
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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