Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEH23348.1PFAM: PhoH-like protein; KEGG: sfu:Sfum_2163 PhoH family protein. (329 aa)    
Predicted Functional Partners:
pdxJ
Metalloprotease ybeY; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. Belongs to the endoribonuclease YbeY family.
  
  
 0.944
recO
DNA repair protein recO; Involved in DNA repair and RecF pathway recombination.
  
  
 0.835
AEH23351.1
RNA methylase, NOL1/NOP2/sun family; KEGG: ton:TON_0716 tRNA/rRNA cytosine-C5-methylase; TIGRFAM: Nop2p; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
     0.835
AEH23349.1
PFAM: Protein of unknown function YGGT; KEGG: din:Selin_0144 hypothetical protein.
       0.813
AEH23350.1
UPF0235 protein yggU; KEGG: swo:Swol_0959 hypothetical protein; HAMAP: Protein of unknown function DUF167; PFAM: Protein of unknown function DUF167; Belongs to the UPF0235 family.
       0.813
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.631
AEH23354.1
KEGG: dak:DaAHT2_0461 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region.
       0.588
AEH23353.1
KEGG: dps:DP1812 biotin carboxylase; PFAM: Carbamoyl phosphate synthase, large subunit, N-terminal; Carbamoyl phosphate synthetase, large subunit, ATP-binding; Biotin carboxylase, C-terminal.
       0.581
AEH23355.1
KEGG: dak:DaAHT2_0462 hypothetical protein.
       0.581
AEH23356.1
KEGG: dak:DaAHT2_0465 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase.
       0.581
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.