| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22350.1 | fdhD | TOPB45_0236 | TOPB45_1409 | Cysteine desulfurase; KEGG: dth:DICTH_0557 aminotransferase, class V superfamily; PFAM: Aminotransferase, class V/Cysteine desulfurase. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.703 |
| AEH22599.1 | AEH22601.1 | TOPB45_0497 | TOPB45_0499 | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | 0.897 |
| AEH22599.1 | AEH22602.1 | TOPB45_0497 | TOPB45_0500 | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.661 |
| AEH22599.1 | AEH23528.1 | TOPB45_0497 | TOPB45_1449 | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |
| AEH22599.1 | fdhD | TOPB45_0497 | TOPB45_1409 | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.543 |
| AEH22601.1 | AEH22599.1 | TOPB45_0499 | TOPB45_0497 | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.897 |
| AEH22601.1 | AEH22602.1 | TOPB45_0499 | TOPB45_0500 | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.877 |
| AEH22601.1 | AEH23528.1 | TOPB45_0499 | TOPB45_1449 | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.804 |
| AEH22601.1 | fdhD | TOPB45_0499 | TOPB45_1409 | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.463 |
| AEH22602.1 | AEH22599.1 | TOPB45_0500 | TOPB45_0497 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.661 |
| AEH22602.1 | AEH22601.1 | TOPB45_0500 | TOPB45_0499 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | PFAM: Formate dehydrogenase accessory protein; KEGG: tye:THEYE_A1302 formate dehydrogenase accessory protein FdhE, putative. | 0.877 |
| AEH22602.1 | fdhD | TOPB45_0500 | TOPB45_1409 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.668 |
| AEH22602.1 | moaA | TOPB45_0500 | TOPB45_1188 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.853 |
| AEH22602.1 | moaC | TOPB45_0500 | TOPB45_0040 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.740 |
| AEH22602.1 | mobA | TOPB45_0500 | TOPB45_0112 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. | 0.961 |
| AEH23489.1 | AEH23491.1 | TOPB45_1408 | TOPB45_1410 | KEGG: sat:SYN_01404 general secretion pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core. | PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: saf:SULAZ_1595 metallo-beta-lactamase family protein. | 0.679 |
| AEH23489.1 | fdhD | TOPB45_1408 | TOPB45_1409 | KEGG: sat:SYN_01404 general secretion pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.756 |
| AEH23491.1 | AEH23489.1 | TOPB45_1410 | TOPB45_1408 | PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: saf:SULAZ_1595 metallo-beta-lactamase family protein. | KEGG: sat:SYN_01404 general secretion pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core. | 0.679 |
| AEH23491.1 | fdhD | TOPB45_1410 | TOPB45_1409 | PFAM: RNA-metabolising metallo-beta-lactamase; KEGG: saf:SULAZ_1595 metallo-beta-lactamase family protein. | Protein fdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. | 0.689 |
| AEH23528.1 | AEH22599.1 | TOPB45_1449 | TOPB45_0497 | TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Formate dehydrogenase, alpha subunit; PFAM: Molybdopterin oxidoreductase Fe4S4 region; Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding region; manually curated; KEGG: tye:THEYE_A0891 formate dehydrogenase, alpha subunit, selenocysteine-containing; TIGRFAM: Formate dehydrogenase, alpha subunit, anaerobic; Twin-arginine translocation pathway, signal sequence; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |