STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (784 aa)    
Predicted Functional Partners:
AEH22359.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 
 0.877
AEH23589.1
Hypothetical protein.
       0.812
AEH23590.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: sat:SYN_00126 pili retraction protein; SMART: ATPase, AAA+ type, core.
       0.812
AEH23591.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: dat:HRM2_04990 PilT1; SMART: ATPase, AAA+ type, core.
       0.812
AEH23588.1
KEGG: ttm:Tthe_2060 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
       0.811
AEH23586.1
KEGG: dal:Dalk_3859 ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpX chaperone family.
 
     0.716
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.674
AEH23584.1
KEGG: sfu:Sfum_3056 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
       0.671
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.669
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family.
       0.656
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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