Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (784 aa)    
Predicted Functional Partners:
AEH22359.1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
  
 
 
 0.875
AEH23589.1
Hypothetical protein.
       0.804
AEH23590.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: sat:SYN_00126 pili retraction protein; SMART: ATPase, AAA+ type, core.
       0.804
AEH23591.1
Twitching motility protein; TIGRFAM: Pilus retraction protein PilT; PFAM: Type II secretion system protein E; KEGG: dat:HRM2_04990 PilT1; SMART: ATPase, AAA+ type, core.
       0.804
AEH23588.1
KEGG: ttm:Tthe_2060 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
       0.802
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
    0.714
AEH23586.1
KEGG: dal:Dalk_3859 ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities, AAA-2; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; Belongs to the ClpX chaperone family.
 
     0.700
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
       0.679
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.673
AEH23584.1
KEGG: sfu:Sfum_3056 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB.
       0.656
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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