Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH23619.1Protein of unknown function DUF101; PFAM: Archease, tRNA m5C methyltransferase chaperone; KEGG: pfu:PF1552 hypothetical protein. (144 aa)    
Predicted Functional Partners:
rtcB
Protein of unknown function UPF0027; PFAM: Uncharacterised protein family UPF0027; KEGG: drt:Dret_0333 hypothetical protein; Belongs to the RtcB family.
 
 0.969
AEH23476.1
Hypothetical protein; KEGG: tye:THEYE_A1962 Uma3.
   
    0.914
der
GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
       0.795
AEH23620.1
KEGG: sep:SE1274 ComEC late competence protein 3; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: ComEC/Rec2-related protein.
       0.757
AEH23621.1
Protein of unknown function UPF0001; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
       0.729
AEH23622.1
5-formyltetrahydrofolate cyclo-ligase; KEGG: dth:DICTH_1097 5,10-methenyltetrahydrofolate synthetase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase.
       0.700
atpC
ATP synthase epsilon chain; Produces ATP from ADP in the presence of a proton gradient across the membrane.
       0.601
atpD
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family.
       0.601
atpG
ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
       0.512
AEH23157.1
KEGG: tam:Theam_1607 ATPase with chaperone activity, ATP-binding subunit.
 
     0.456
Your Current Organism:
Thermodesulfobacterium geofontis
NCBI taxonomy Id: 795359
Other names: T. geofontis OPF15, Thermodesulfobacterium geofontis OPF15, Thermodesulfobacterium sp. OPF15
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