| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEH22307.1 | argH | TOPB45_0192 | TOPB45_1620 | KEGG: tam:Theam_1017 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal. | PFAM: Fumarate lyase; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: dte:Dester_1517 argininosuccinate lyase. | 0.913 |
| AEH22307.1 | mdh | TOPB45_0192 | TOPB45_0217 | KEGG: tam:Theam_1017 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.845 |
| AEH23604.1 | AEH23710.1 | TOPB45_1526 | TOPB45_1632 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.408 |
| AEH23604.1 | argB | TOPB45_1526 | TOPB45_1036 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.946 |
| AEH23604.1 | argC | TOPB45_1526 | TOPB45_0717 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.461 |
| AEH23604.1 | argD | TOPB45_1526 | TOPB45_0138 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: slp:Slip_2175 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.436 |
| AEH23604.1 | argG | TOPB45_1526 | TOPB45_0486 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: tsc:TSC_c02740 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.697 |
| AEH23604.1 | argH | TOPB45_1526 | TOPB45_1620 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | PFAM: Fumarate lyase; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: dte:Dester_1517 argininosuccinate lyase. | 0.941 |
| AEH23604.1 | argJ | TOPB45_1526 | TOPB45_0529 | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.941 |
| AEH23702.1 | argH | TOPB45_1624 | TOPB45_1620 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: saf:SULAZ_0637 fumarate hydratase, class I; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | PFAM: Fumarate lyase; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: dte:Dester_1517 argininosuccinate lyase. | 0.848 |
| AEH23702.1 | mdh | TOPB45_1624 | TOPB45_0217 | Hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; TIGRFAM: Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: saf:SULAZ_0637 fumarate hydratase, class I; PFAM: Fe-S type hydro-lyases tartrate/fumarate beta region. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.965 |
| AEH23710.1 | AEH23604.1 | TOPB45_1632 | TOPB45_1526 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | 0.408 |
| AEH23710.1 | argB | TOPB45_1632 | TOPB45_1036 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.950 |
| AEH23710.1 | argC | TOPB45_1632 | TOPB45_0717 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.937 |
| AEH23710.1 | argD | TOPB45_1632 | TOPB45_0138 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: slp:Slip_2175 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.931 |
| AEH23710.1 | argG | TOPB45_1632 | TOPB45_0486 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; HAMAP: Argininosuccinate synthase; KEGG: tsc:TSC_c02740 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.994 |
| AEH23710.1 | argH | TOPB45_1632 | TOPB45_1620 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | PFAM: Fumarate lyase; TIGRFAM: Argininosuccinate lyase; HAMAP: Argininosuccinate lyase; KEGG: dte:Dester_1517 argininosuccinate lyase. | 0.945 |
| AEH23710.1 | argJ | TOPB45_1632 | TOPB45_0529 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | Arginine biosynthesis bifunctional protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.992 |
| argB | AEH23604.1 | TOPB45_1036 | TOPB45_1526 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: GCN5-related N-acetyltransferase; KEGG: tye:THEYE_A1043 bifunctional protein argHA; Belongs to the acetyltransferase family. | 0.946 |
| argB | AEH23710.1 | TOPB45_1036 | TOPB45_1632 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. | 0.950 |