slc9a3r1a protein (Danio rerio) - STRING interaction network

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slc9a3r1a

Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (384 aa)

Predicted Functional Partners:

cftr

0.993

msna

0.974

ezrb

0.974

ezra

0.947

msnb

0.901

podxl

0.886

suox

0.872

nf2a

0.755

sgk1

0.743

nf2b

0.722

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cftr	ezra	ENSDARP00000060242	ENSDARP00000108896	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ezrl protein.	0.489
cftr	ezrb	ENSDARP00000060242	ENSDARP00000073352	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Ezrin b.	0.618
cftr	msna	ENSDARP00000060242	ENSDARP00000017246	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Moesin a.	0.580
cftr	slc9a3r1a	ENSDARP00000060242	ENSDARP00000000069	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.993
cftr	suox	ENSDARP00000060242	ENSDARP00000135810	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	Sulfite oxidase.	0.519
ezra	cftr	ENSDARP00000108896	ENSDARP00000060242	Ezrl protein.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.489
ezra	msna	ENSDARP00000108896	ENSDARP00000017246	Ezrl protein.	Moesin a.	0.866
ezra	msnb	ENSDARP00000108896	ENSDARP00000105041	Ezrl protein.	Moesin b.	0.639
ezra	podxl	ENSDARP00000108896	ENSDARP00000093077	Ezrl protein.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.452
ezra	slc9a3r1a	ENSDARP00000108896	ENSDARP00000000069	Ezrl protein.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.947
ezrb	cftr	ENSDARP00000073352	ENSDARP00000060242	Ezrin b.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.618
ezrb	msna	ENSDARP00000073352	ENSDARP00000017246	Ezrin b.	Moesin a.	0.957
ezrb	msnb	ENSDARP00000073352	ENSDARP00000105041	Ezrin b.	Moesin b.	0.830
ezrb	podxl	ENSDARP00000073352	ENSDARP00000093077	Ezrin b.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.582
ezrb	slc9a3r1a	ENSDARP00000073352	ENSDARP00000000069	Ezrin b.	Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.	0.974
msna	cftr	ENSDARP00000017246	ENSDARP00000060242	Moesin a.	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelia [...]	0.580
msna	ezra	ENSDARP00000017246	ENSDARP00000108896	Moesin a.	Ezrl protein.	0.866
msna	ezrb	ENSDARP00000017246	ENSDARP00000073352	Moesin a.	Ezrin b.	0.957
msna	msnb	ENSDARP00000017246	ENSDARP00000105041	Moesin a.	Moesin b.	0.813
msna	podxl	ENSDARP00000017246	ENSDARP00000093077	Moesin a.	Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family.	0.748

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