Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
adam8aA disintegrin and metalloproteinase domain 8a. (843 aa)    
Predicted Functional Partners:
F1QCI4_DANRE
Si:ch211-264f5.2.
   
  
 0.616
mmp9
Matrix metallopeptidase 9.
   
  
 0.573
pwwp2b
PWWP domain-containing 2B.
      
 0.501
adam10a
ADAM metallopeptidase domain 10a.
     
0.498
asb12a
Ankyrin repeat and SOCS box-containing 12a.
      
 0.485
stx11a
Syntaxin 11a; Belongs to the syntaxin family.
   
  
 0.475
adam17b
ADAM metallopeptidase domain 17b.
     
0.466
smim13
Small integral membrane protein 13.
      
 0.465
rbm12
RNA-binding motif protein 12.
      
 0.460
nlrp16
NACHT, LRR and PYD domains-containing protein 16.
    
 
 0.445
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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