pms1 protein (Danio rerio) - STRING interaction network

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Score

pms1

PMS1 homolog 1, mismatch repair system component. (896 aa)

Predicted Functional Partners:

msh2

0.991

mlh1

0.988

msh6

0.987

msh3

0.969

exo1

0.947

msh4

0.938

pms2

0.915

mlh3

0.914

msh5

0.902

polk

0.889

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
exo1	mlh1	ENSDARP00000073846	ENSDARP00000113460	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	0.981
exo1	mlh3	ENSDARP00000073846	ENSDARP00000120332	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	MutL homolog 3 (E. coli).	0.803
exo1	msh2	ENSDARP00000073846	ENSDARP00000027768	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.983
exo1	msh3	ENSDARP00000073846	ENSDARP00000086717	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.960
exo1	msh4	ENSDARP00000073846	ENSDARP00000127531	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	MutS homolog 4.	0.858
exo1	msh5	ENSDARP00000073846	ENSDARP00000129461	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	MutS homolog 5.	0.787
exo1	msh6	ENSDARP00000073846	ENSDARP00000131172	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.984
exo1	pms1	ENSDARP00000073846	ENSDARP00000001250	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	PMS1 homolog 1, mismatch repair system component.	0.947
exo1	pms2	ENSDARP00000073846	ENSDARP00000099444	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	PMS1 homolog 2, mismatch repair system component.	0.992
exo1	polk	ENSDARP00000073846	ENSDARP00000078372	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	Polymerase (DNA directed) kappa.	0.847
mlh1	exo1	ENSDARP00000113460	ENSDARP00000073846	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	0.981
mlh1	mlh3	ENSDARP00000113460	ENSDARP00000120332	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	MutL homolog 3 (E. coli).	0.997
mlh1	msh2	ENSDARP00000113460	ENSDARP00000027768	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.999
mlh1	msh3	ENSDARP00000113460	ENSDARP00000086717	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR).	0.991
mlh1	msh4	ENSDARP00000113460	ENSDARP00000127531	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	MutS homolog 4.	0.922
mlh1	msh5	ENSDARP00000113460	ENSDARP00000129461	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	MutS homolog 5.	0.902
mlh1	msh6	ENSDARP00000113460	ENSDARP00000131172	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.998
mlh1	pms1	ENSDARP00000113460	ENSDARP00000001250	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	PMS1 homolog 1, mismatch repair system component.	0.988
mlh1	pms2	ENSDARP00000113460	ENSDARP00000099444	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).	PMS1 homolog 2, mismatch repair system component.	0.999
mlh3	exo1	ENSDARP00000120332	ENSDARP00000073846	MutL homolog 3 (E. coli).	Exonuclease 1; 5'->3' double-stranded DNA exonuclease which may also contain a cryptic 3'->5' double-stranded DNA exonuclease activity. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for DNA mismatch repair (MMR) (By similarity).	0.803

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