hsd17b8 protein (Danio rerio) - STRING interaction network

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Score

hsd17b8

FabG (Beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like. (256 aa)

Predicted Functional Partners:

cbr4

0.999

oxsm

0.986

hsd17b7

0.982

hsd17b3

0.979

hsd17b1

0.978

cyp17a2

0.970

hsd11b1la

0.965

hsd17b2

0.965

hsd20b2

0.963

cyp19a1a

0.963

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cbr4	cyp19a1a	ENSDARP00000010074	ENSDARP00000111604	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.439
cbr4	hsd11b1la	ENSDARP00000010074	ENSDARP00000061738	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid 11-beta-dehydrogenase 1-like protein.	0.425
cbr4	hsd17b3	ENSDARP00000010074	ENSDARP00000124637	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.620
cbr4	hsd17b8	ENSDARP00000010074	ENSDARP00000001459	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	FabG (Beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like.	0.999
cbr4	hsd20b2	ENSDARP00000010074	ENSDARP00000091542	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	20beta-hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.535
cbr4	oxsm	ENSDARP00000010074	ENSDARP00000137981	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.983
cyp17a2	cyp19a1a	ENSDARP00000070565	ENSDARP00000111604	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	0.976
cyp17a2	hsd11b1la	ENSDARP00000070565	ENSDARP00000061738	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Hydroxysteroid 11-beta-dehydrogenase 1-like protein.	0.967
cyp17a2	hsd17b1	ENSDARP00000070565	ENSDARP00000026566	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.967
cyp17a2	hsd17b2	ENSDARP00000070565	ENSDARP00000066984	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.968
cyp17a2	hsd17b3	ENSDARP00000070565	ENSDARP00000124637	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.974
cyp17a2	hsd17b7	ENSDARP00000070565	ENSDARP00000098015	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	Hydroxysteroid (17-beta) dehydrogenase 7.	0.939
cyp17a2	hsd17b8	ENSDARP00000070565	ENSDARP00000001459	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	FabG (Beta-ketoacyl-[acyl-carrier-protein] reductase, E. coli) like.	0.970
cyp17a2	hsd20b2	ENSDARP00000070565	ENSDARP00000091542	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	20beta-hydroxysteroid dehydrogenase type 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.979
cyp19a1a	cbr4	ENSDARP00000111604	ENSDARP00000010074	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Carbonyl reductase family member 4; The heterotetramer with HSD17B8 has NADH-dependent 3- ketoacyl-acyl carrier protein reductase activity, and thereby plays a role in mitochondrial fatty acid biosynthesis. Within the heterotetramer, HSD17B8 binds NADH; CBR4 binds NADPD. The homotetramer has NADPH-dependent quinone reductase activity. Both homotetramer and the heterotetramer have broad in vitro substrate specificity and can reduce 9,10-phenanthrenequinone, 1,4-benzoquinone and various other o- quinones and p-quinones; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.439
cyp19a1a	cyp17a2	ENSDARP00000111604	ENSDARP00000070565	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Cytochrome P450, family 17, subfamily A, polypeptide 2; Belongs to the cytochrome P450 family.	0.976
cyp19a1a	hsd11b1la	ENSDARP00000111604	ENSDARP00000061738	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid 11-beta-dehydrogenase 1-like protein.	0.625
cyp19a1a	hsd17b1	ENSDARP00000111604	ENSDARP00000026566	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid (17-beta) dehydrogenase 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.994
cyp19a1a	hsd17b2	ENSDARP00000111604	ENSDARP00000066984	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid (17-beta) dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.982
cyp19a1a	hsd17b3	ENSDARP00000111604	ENSDARP00000124637	Aromatase; Catalyzes the formation of aromatic C18 estrogens from C19 androgens.	Hydroxysteroid (17-beta) dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.991

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