Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dhx16DEAH (Asp-Glu-Ala-His) box polypeptide 16. (1054 aa)    
Predicted Functional Partners:
gpkow
G-patch domain and KOW motifs-containing protein; RNA-binding protein involved in pre-mRNA splicing. Belongs to the MOS2 family.
    
 
 0.991
xab2
Similar to Xab2 protein.
   
 
 0.980
sf3b2
Splicing factor 3b, subunit 2.
   
 
 0.977
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38.
  
 
0.974
ppil4
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
   
 
 0.970
bud13
BUD13 homolog.
   
 
 0.950
cdc40
Cell division cycle 40 homolog (S. cerevisiae).
   
 
 0.935
prpf8
Pre-mRNA-processing factor 8.
   
 
 0.927
sf3b3
Splicing factor 3B subunit 3; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mR [...]
   
 
 0.927
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
   
 
 0.923
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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