Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
upb1Ureidopropionase, beta. (384 aa)    
Predicted Functional Partners:
agxt2
Alanine--glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.990
dpys
Dihydropyrimidinase.
 
 
 0.988
abat
4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.979
aldh7a1
Aldehyde dehydrogenase 7 family, member A1; Belongs to the aldehyde dehydrogenase family.
   
 0.970
cndp2
Carnosine dipeptidase 2.
  
 
 0.969
aldh3a2b
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.958
aldh3a1
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 0.958
aldh9a1b
4-trimethylaminobutyraldehyde dehydrogenase B; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.
   
 0.957
aldh16a1
Aldehyde dehydrogenase 16 family, member A1.
   
 0.957
gad2
Glutamate decarboxylase 2.
  
 
 0.955
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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