STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
epha4lEph receptor A4,-like. (988 aa)    
Predicted Functional Partners:
myo5ab
Myosin VAb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.731
efna5b
Ephrin-A5b; Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the epha3 receptor [...]
   
 0.684
efnb3b
Efnb3 protein; Belongs to the ephrin family.
   
 0.669
efnb2b
Ephrin-B2b; Belongs to the ephrin family.
   
 0.669
efnb1
Ephrin-B1; Belongs to the ephrin family.
   
 0.664
efna2b
Ephrin-A2b; Belongs to the ephrin family.
   
 0.643
efna1b
Ephrin A-L1; Belongs to the ephrin family.
   
 0.627
efna3b
Ephrin-A3b; Belongs to the ephrin family.
   
 0.616
ENSDARP00000152912
Si:dkey-246i14.3; Belongs to the ephrin family.
   
 0.609
astn1
Astrotactin 1.
   
 
 0.597
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.