STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vac14Protein VAC14 homolog; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity (By similarity). (771 aa)    
Predicted Functional Partners:
FIG4
FIG4 phosphoinositide 5-phosphatase.
    
 
 0.996
pikfyve
Phosphatidylinositol phosphate 5-kinase type III isoform d.
   
 
 0.995
Fig4b
Uncharacterized protein.
    
 
 0.916
rad54l
RAD54-like.
 
  
   0.901
rad54b
RAD54 homolog B.
 
  
   0.847
dipk2aa
Divergent protein kinase domain 2Aa.
    
 
 0.805
dipk2ab
Divergent protein kinase domain 2Ab.
    
 
 0.805
pik3c3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 
 0.779
tmem86a
Transmembrane protein 86A.
      
 0.757
wipi1
WD repeat domain, phosphoinositide-interacting 1.
    
 
 0.736
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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