STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmx1Thioredoxin-related transmembrane protein 1. (284 aa)    
Predicted Functional Partners:
trmt1l
tRNA methyltransferase 1-like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
    
 
 0.863
ccdc90b
Coiled-coil domain-containing 90B.
      
 0.749
dnaaf2
Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. Belongs to the PIH1 family. Kintoun subfamily.
    
 
 0.731
lrrc59
Leucine-rich repeat-containing protein 59; Required for nuclear import of FGF1.
   
 
 0.615
bcap31
Novel protein similar to vertebrate caldesmon 1 (CALD1).
    
 
 0.598
txndc12
Thioredoxin domain-containing 12 (endoplasmic reticulum).
   
 
 0.596
calua
Calumenin-A; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma- carboxylase ggcx. Binds 7 calcium ions with a low affinity (By similarity).
   
 
 0.583
pkdccb
Protein kinase domain-containing, cytoplasmic b.
    
 
 0.582
btbd2a
BTB (POZ) domain-containing 2a.
   
  
 0.573
pdia5
Protein disulfide isomerase family A, member 5.
   
  
 0.573
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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