STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
xpo4Exportin-4; Mediates the nuclear export of proteins (cargos) with broad substrate specificity; Belongs to the exportin family. (1150 aa)    
Predicted Functional Partners:
eif5a2
Eukaryotic translation initiation factor 5A.
   
 
 0.934
eif5a
Eukaryotic translation initiation factor 5A.
    
 
 0.915
xpot
Exportin-T; Mediates the nuclear export of aminoacylated tRNAs. Belongs to the exportin family.
   
  
 0.896
xpo6
Exportin-6; Mediates the nuclear export of actin and profilin-actin complexes in somatic cells; Belongs to the exportin family.
   
  
 0.810
ipo13
Importin 13.
    
 
 0.806
ipo11
Importin 11.
      
 0.801
cse1l
Exportin-2; Export receptor for importin alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm (By similarity). Negatively regulates fluid secretion and plays a role in fluid homeostasis by downregulating cftr activity.
   
  
 0.782
xpo7
Exportin 7.
   
  
0.768
thoc2
THO complex 2.
    
 
 0.764
tnpo2
Transportin 2 (Importin 3, Karyopherin beta 2b).
   
  
 0.701
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.