node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PARD3 | llgl2 | ENSDARP00000155112 | ENSDARP00000035593 | Par-3 family cell polarity regulator. | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | 0.481 |
PARD3 | mpp5a | ENSDARP00000155112 | ENSDARP00000123304 | Par-3 family cell polarity regulator. | MAGUK p55 subfamily member 5-A; Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells (By similarity). Also involved in adherens junction biogenesis (By similarity). Functions in cellular patterning of the retina. | 0.788 |
PARD3 | pard3ab | ENSDARP00000155112 | ENSDARP00000108968 | Par-3 family cell polarity regulator. | Par-3 family cell polarity regulator alpha, b. | 0.904 |
PARD3 | pard6a | ENSDARP00000155112 | ENSDARP00000091677 | Par-3 family cell polarity regulator. | Par-6 family cell polarity regulator alpha. | 0.941 |
PARD3 | pard6b | ENSDARP00000155112 | ENSDARP00000008287 | Par-3 family cell polarity regulator. | Par-6 partitioning defective 6 homolog beta (C. elegans). | 0.890 |
PARD3 | pard6ga | ENSDARP00000155112 | ENSDARP00000124147 | Par-3 family cell polarity regulator. | Par-6 family cell polarity regulator gamma a. | 0.891 |
PARD3 | pard6gb | ENSDARP00000155112 | ENSDARP00000052392 | Par-3 family cell polarity regulator. | Par-6 partitioning defective 6-like protein gamma. | 0.910 |
PARD3 | prkci | ENSDARP00000155112 | ENSDARP00000005309 | Par-3 family cell polarity regulator. | Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway (By similarity). Is required for the formation and maintenance of the zonula adherens during early epithelial development and plays a critical role in organ morphogenesis and in regulating the orientation of cell division. | 0.988 |
llgl1 | llgl2 | ENSDARP00000093316 | ENSDARP00000035593 | LLGL scribble cell polarity complex component 1. | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | 0.905 |
llgl1 | pard3ab | ENSDARP00000093316 | ENSDARP00000108968 | LLGL scribble cell polarity complex component 1. | Par-3 family cell polarity regulator alpha, b. | 0.486 |
llgl1 | pard6a | ENSDARP00000093316 | ENSDARP00000091677 | LLGL scribble cell polarity complex component 1. | Par-6 family cell polarity regulator alpha. | 0.511 |
llgl1 | pard6b | ENSDARP00000093316 | ENSDARP00000008287 | LLGL scribble cell polarity complex component 1. | Par-6 partitioning defective 6 homolog beta (C. elegans). | 0.562 |
llgl1 | pard6ga | ENSDARP00000093316 | ENSDARP00000124147 | LLGL scribble cell polarity complex component 1. | Par-6 family cell polarity regulator gamma a. | 0.511 |
llgl1 | pard6gb | ENSDARP00000093316 | ENSDARP00000052392 | LLGL scribble cell polarity complex component 1. | Par-6 partitioning defective 6-like protein gamma. | 0.563 |
llgl1 | prkci | ENSDARP00000093316 | ENSDARP00000005309 | LLGL scribble cell polarity complex component 1. | Protein kinase C iota type; Calcium- and diacylglycerol-independent serine/ threonine- protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway (By similarity). Is required for the formation and maintenance of the zonula adherens during early epithelial development and plays a critical role in organ morphogenesis and in regulating the orientation of cell division. | 0.967 |
llgl2 | PARD3 | ENSDARP00000035593 | ENSDARP00000155112 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | Par-3 family cell polarity regulator. | 0.481 |
llgl2 | llgl1 | ENSDARP00000035593 | ENSDARP00000093316 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | LLGL scribble cell polarity complex component 1. | 0.905 |
llgl2 | pard3ab | ENSDARP00000035593 | ENSDARP00000108968 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | Par-3 family cell polarity regulator alpha, b. | 0.576 |
llgl2 | pard6a | ENSDARP00000035593 | ENSDARP00000091677 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | Par-6 family cell polarity regulator alpha. | 0.796 |
llgl2 | pard6b | ENSDARP00000035593 | ENSDARP00000008287 | LLGL scribble cell polarity complex component 2; Essential for hemidesmosome formation and maintenance of the cytoskeleton elements as well as cellular morphology in the basal epidermis during development. Also involved in regulating growth of the basal epidermis; Belongs to the WD repeat L(2)GL family. | Par-6 partitioning defective 6 homolog beta (C. elegans). | 0.829 |