STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lft1Left-right determination factor; Belongs to the TGF-beta family. (358 aa)    
Predicted Functional Partners:
ndr1
Nodal-related 1.
  
 
 0.996
spaw
Southpaw.
  
 
 0.996
tdgf1
Teratocarcinoma-derived growth factor 1.
   
 
 0.934
lft2
Left-right determination factor.
  
 
0.925
tgfb3
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.906
tgfb1a
Transforming growth factor beta; Belongs to the TGF-beta family.
     
0.903
tgfb5
Transforming growth factor beta; Belongs to the TGF-beta family.
     
 0.903
tgfb1b
Transforming growth factor beta; Belongs to the TGF-beta family.
     
0.903
tgfb2
Transforming growth factor, beta 2.
     
0.903
pitx2
Pituitary homeobox 2; Isoform a and isoform c differentially regulate mesendoderm formation and asymmetric organ development. Both isoforms regulate left-right development, but isoform a has a stronger effect on heart laterality; Belongs to the paired homeobox family. Bicoid subfamily.
   
  
 0.874
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.