STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
wnt10aProtein Wnt-10a; Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Required for normal tooth development. Regulates the expression of genes involved in tooth development. Belongs to the Wnt family. (442 aa)    
Predicted Functional Partners:
fzd1
Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.873
wif1
Wnt inhibitory factor 1; Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
    
 0.854
fzd4
Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.849
fzd5
Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.
   
 0.845
sfrp1a
Secreted frizzled-related protein 1a.
    
 0.843
fzd2
Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.843
sfrp2
Secreted frizzled-related protein 2.
    
 0.838
fzd6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.838
lrp5
Low density lipoprotein receptor-related protein 5.
   
 0.830
sfrp5
Secreted frizzled-related protein 5.
   
 0.822
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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