STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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[Homology]
Score
engaseMannosyl-glycoprotein endo-beta-n-acetylglucosaminidase; Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol (By similarity) (724 aa)    
Predicted Functional Partners:
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1
     
  0.900
ubb
Polyubiquitin-c; Ubiquitin C
     
 0.900
rps27a
Ubiquitin-small subunit ribosomal protein s27ae; Ribosomal protein S27a
     
  0.900
entpd3
Ectonucleoside triphosphate diphosphohydrolase 3; Belongs to the GDA1/CD39 NTPase family
      
 0.844
tpbgb
Trophoblast glycoprotein b precursor; Wnt-activated inhibitory factor 1c; Trophoblast glycoprotein b
   
  
 0.823
tssc1
EARP-interacting protein homolog; Tumor suppressing subtransferable candidate 1; Belongs to the WD repeat EIPR1 family
   
  
 0.756
manba
Mannosidase, beta A, lysosomal
     
 0.699
ENSDARP00000104247
Mannosidase, beta A, lysosomal
     
 0.699
fra10ac1
Protein fra10ac1; FRA10A-associated CGG repeat 1; Fragile site, folic acid type, rare, candidate 1
      
 0.689
ngly1
Peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase; Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native protein [...]
   
  
 0.685
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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