Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
eya2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (475 aa)    
Predicted Functional Partners:
hbl2
Hexose-binding lectin 2.
      
 0.800
six2a
Sine oculis homeobox homolog 2.1.
   
 
 0.756
E7F4P0_DANRE
Si:dkey-210j14.4.
    
 
 0.664
dacha
Dachshund a.
    
 
 0.623
dachc
Dachshund c.
    
 
 0.623
dachb
Dachshund b.
    
 
 0.623
dachd
Dachshund d.
    
 
 0.623
B0UYN8_DANRE
Si:dkey-57a22.14; Belongs to the beta/gamma-crystallin family.
      
 0.621
E7FCV0_DANRE
Si:dkey-185e18.7.
      
 0.594
zwilch
Protein zwilch homolog; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and mad1-mad2 complexes onto kinetochores (By similarity).
      
 0.590
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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