node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
brf1a | brf2 | ENSDARP00000029653 | ENSDARP00000130569 | BRF1 RNA polymerase III transcription initiation factor subunit a. | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | 0.933 |
brf1a | gtf3c3 | ENSDARP00000029653 | ENSDARP00000112332 | BRF1 RNA polymerase III transcription initiation factor subunit a. | General transcription factor IIIC, polypeptide 3. | 0.968 |
brf1a | polr1c | ENSDARP00000029653 | ENSDARP00000112094 | BRF1 RNA polymerase III transcription initiation factor subunit a. | RNA polymerase I and III subunit C. | 0.888 |
brf1a | polr2k | ENSDARP00000029653 | ENSDARP00000099037 | BRF1 RNA polymerase III transcription initiation factor subunit a. | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.896 |
brf1a | polr3a | ENSDARP00000029653 | ENSDARP00000139214 | BRF1 RNA polymerase III transcription initiation factor subunit a. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.932 |
brf1a | polr3b | ENSDARP00000029653 | ENSDARP00000085899 | BRF1 RNA polymerase III transcription initiation factor subunit a. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.932 |
brf1a | polr3c | ENSDARP00000029653 | ENSDARP00000059966 | BRF1 RNA polymerase III transcription initiation factor subunit a. | DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). | 0.889 |
brf1a | polr3f | ENSDARP00000029653 | ENSDARP00000004882 | BRF1 RNA polymerase III transcription initiation factor subunit a. | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. | 0.958 |
brf1a | tbp | ENSDARP00000029653 | ENSDARP00000010211 | BRF1 RNA polymerase III transcription initiation factor subunit a. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity). Members of the TBP family are differentially required for transcription and development during early embryogenesis. Regulates mRNA levels in the early embryo by both transcriptional and post-transcriptional mechanisms. Required for transcription of a subs [...] | 0.972 |
brf1a | zgc:162472 | ENSDARP00000029653 | ENSDARP00000125788 | BRF1 RNA polymerase III transcription initiation factor subunit a. | Zgc:162472. | 0.965 |
brf2 | brf1a | ENSDARP00000130569 | ENSDARP00000029653 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | BRF1 RNA polymerase III transcription initiation factor subunit a. | 0.933 |
brf2 | gtf3c3 | ENSDARP00000130569 | ENSDARP00000112332 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | General transcription factor IIIC, polypeptide 3. | 0.923 |
brf2 | polr1c | ENSDARP00000130569 | ENSDARP00000112094 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | RNA polymerase I and III subunit C. | 0.836 |
brf2 | polr2k | ENSDARP00000130569 | ENSDARP00000099037 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | Polymerase (RNA) II (DNA directed) polypeptide K. | 0.818 |
brf2 | polr3a | ENSDARP00000130569 | ENSDARP00000139214 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.914 |
brf2 | polr3b | ENSDARP00000130569 | ENSDARP00000085899 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.926 |
brf2 | polr3c | ENSDARP00000130569 | ENSDARP00000059966 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | DNA-directed RNA polymerase III subunit RPC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs (By similarity). | 0.831 |
brf2 | polr3f | ENSDARP00000130569 | ENSDARP00000004882 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. | 0.904 |
brf2 | tbp | ENSDARP00000130569 | ENSDARP00000010211 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (By similarity). Members of the TBP family are differentially required for transcription and development during early embryogenesis. Regulates mRNA levels in the early embryo by both transcriptional and post-transcriptional mechanisms. Required for transcription of a subs [...] | 0.964 |
brf2 | zgc:162472 | ENSDARP00000130569 | ENSDARP00000125788 | Transcription factor IIIB 50 kDa subunit; General activator of RNA polymerase III transcription. Factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites. Contributes to the regulation of gene expression; functions as activator in the absence of oxidative stress. Down-regulates expression of target genes in response to oxidative stress. Overexpression protects cells against apoptosis in response to oxidative stress; Belongs to the TFIIB family. | Zgc:162472. | 0.941 |