STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmem237aTransmembrane protein 237A; Component of the transition zone in primary cilia. Required for ciliogenesis. (377 aa)    
Predicted Functional Partners:
arr3b
Arrestin 3b, retinal (X-arrestin).
   
 
 0.709
kcnv2b
Potassium channel, subfamily V, member 2b; Belongs to the potassium channel family.
   
 
 0.641
rom1b
Retinal outer segment membrane protein 1b.
   
  
 0.569
tmem231
Transmembrane protein 231; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
      
 0.557
mapk10
Mitogen-activated protein kinase.
      
 0.545
arr3a
Arrestin 3, retinal (X-arrestin), like.
   
 
 0.541
kcnv2a
Potassium channel, subfamily V, member 2a; Belongs to the potassium channel family.
   
 
 0.540
nphp1
Nephronophthisis 1.
   
 
 0.531
polr2f
Polymerase (RNA) II (DNA directed) polypeptide F.
  
  
 0.523
zgc:174895
Zgc:174895.
  
 
 0.504
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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