stard3 protein (Danio rerio) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

stard3

StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes. (448 aa)

Predicted Functional Partners:

top1mt-2

0.991

vapb

0.984

mospd2

0.938

vdac1

0.933

star

0.912

stard3nl

0.907

pctp

0.843

zfyve27

0.832

stard7

0.826

cert1a

0.824

Your Current Organism:

Danio rerio

NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cert1a	mospd2	ENSDARP00000124594	ENSDARP00000034076	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	Motile sperm domain-containing 2.	0.717
cert1a	pctp	ENSDARP00000124594	ENSDARP00000097884	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	Phosphatidylcholine transfer protein.	0.736
cert1a	star	ENSDARP00000124594	ENSDARP00000023907	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).	0.618
cert1a	stard3	ENSDARP00000124594	ENSDARP00000007948	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.	0.824
cert1a	stard3nl	ENSDARP00000124594	ENSDARP00000066788	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	STARD3 N-terminal-like.	0.412
cert1a	stard7	ENSDARP00000124594	ENSDARP00000122941	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	StAR-related lipid transfer (START) domain-containing 7.	0.703
cert1a	top1mt-2	ENSDARP00000124594	ENSDARP00000139898	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	DNA topoisomerase I mitochondrial.	0.736
cert1a	vapb	ENSDARP00000124594	ENSDARP00000094134	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	VAMP (vesicle-associated membrane protein)-associated protein B and C.	0.788
mospd2	cert1a	ENSDARP00000034076	ENSDARP00000124594	Motile sperm domain-containing 2.	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	0.717
mospd2	stard3	ENSDARP00000034076	ENSDARP00000007948	Motile sperm domain-containing 2.	StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.	0.938
mospd2	stard3nl	ENSDARP00000034076	ENSDARP00000066788	Motile sperm domain-containing 2.	STARD3 N-terminal-like.	0.767
mospd2	top1mt-2	ENSDARP00000034076	ENSDARP00000139898	Motile sperm domain-containing 2.	DNA topoisomerase I mitochondrial.	0.762
mospd2	vapb	ENSDARP00000034076	ENSDARP00000094134	Motile sperm domain-containing 2.	VAMP (vesicle-associated membrane protein)-associated protein B and C.	0.501
mospd2	zfyve27	ENSDARP00000034076	ENSDARP00000113701	Motile sperm domain-containing 2.	Zinc finger, FYVE domain-containing 27.	0.532
pctp	cert1a	ENSDARP00000097884	ENSDARP00000124594	Phosphatidylcholine transfer protein.	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	0.736
pctp	star	ENSDARP00000097884	ENSDARP00000023907	Phosphatidylcholine transfer protein.	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).	0.588
pctp	stard3	ENSDARP00000097884	ENSDARP00000007948	Phosphatidylcholine transfer protein.	StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.	0.843
star	cert1a	ENSDARP00000023907	ENSDARP00000124594	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).	Ceramide transfer protein; Shelters ceramides and diacylglycerol lipids inside its START domain and mediates the intracellular trafficking of ceramides and diacylglycerol lipids in a non-vesicular manner (By similarity). Isoform 1 plays a role in neural development and skeletal muscle development. Negatively regulates apoptosis during development.	0.618
star	pctp	ENSDARP00000023907	ENSDARP00000097884	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).	Phosphatidylcholine transfer protein.	0.588
star	stard3	ENSDARP00000023907	ENSDARP00000007948	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).	StAR-related lipid transfer protein 3; Sterol-binding protein that mediates cholesterol transport from the endoplasmic reticulum to endosomes. Creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum. Acts as a lipid transfer protein that redirects sterol to the endosome at the expense of the cell membrane and favors membrane formation inside endosomes.	0.912

page 1 of 4

Server load: low (12%) [HD]

Permalink

Network

Co-occurrence

Experiments

Co-expression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About