Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
drg2Developmentally-regulated GTP-binding protein 2. (364 aa)    
Predicted Functional Partners:
rwdd1
RWD domain-containing 1.
   
 0.998
gcn1
GCN1 activator of EIF2AK4.
   
 
 0.934
zc3h15
Zinc finger CCCH domain-containing protein 15; Protects drg1 from proteolytic degradation.
   
 
 0.922
drg1
Developmentally-regulated GTP-binding protein 1.
  
  
0.885
eapp
E2f-associated phosphoprotein.
   
  
 0.833
rell1
RELT-like 1.
   
 
 0.828
rwdd
RWD domain-containing 4.
   
 
 0.828
arfgef3
ARFGEF family member 3.
      
 0.794
ddx56
DEAD (Asp-Glu-Ala-Asp) box helicase 56.
   
   0.788
psip1a
PC4 and SFRS1-interacting protein 1a.
    
 
 0.786
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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