Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
stk17alSerine/threonine kinase 17a-like. (358 aa)    
Predicted Functional Partners:
btg1
B-cell translocation gene 1, anti-proliferative.
   
  
 0.806
sec22ba
Vesicle-trafficking protein SEC22b-A; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
      
 0.720
mcl1a
MCL1 apoptosis regulator, BCL2 family member a.
   
  
 0.681
psip1a
PC4 and SFRS1-interacting protein 1a.
      
 0.585
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b.
 
      0.564
fam49ba
Family with sequence similarity 49 member Ba.
      
 0.558
nme5
NME/NM23 family member 5; Belongs to the NDK family.
    
 
 0.537
kalrna
Kalirin RhoGEF kinase a.
 
  
   0.536
chp1
Calcineurin-like EF-hand protein 1.
    
  0.523
s100a11
S100 calcium-binding protein A11.
      
 0.503
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (14%) [HD]