Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
xab2Similar to Xab2 protein. (851 aa)    
Predicted Functional Partners:
syf2
Pre-mRNA-splicing factor syf2; Involved in pre-mRNA splicing as component of the spliceosome.
    
 0.999
prpf19
PRP19/PSO4 homolog (S. cerevisiae).
   
 0.999
crnkl1
Crooked neck pre-mRNA-splicing factor 1.
   
0.999
plrg1
Pleiotropic regulator 1.
   
 0.998
cdc5l
CDC5 cell division cycle 5-like (S. pombe).
   
 0.998
aqr
Aquarius intron-binding spliceosomal factor.
   
 0.998
cwc22
Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly.
   
 0.997
snw1
SNW domain-containing 1.
   
 0.997
rbm22
Pre-mRNA-splicing factor RBM22; Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle (By similarity). Required for normal early embryogenesis.
   
 0.996
isy1
ISY1-splicing factor homolog.
    
 0.996
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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