STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpr183aG-protein coupled receptor 183-A; G-protein coupled receptor expressed in lymphocytes that acts as a chemotactic receptor for B-cells, T-cells, splenic dendritic cells, monocytes/macrophages and astrocytes (By similarity). Receptor for oxysterol 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC) and other related oxysterols (By similarity). Mediates cell positioning and movement of a number of cells by binding the 7-alpha,25-OHC ligand that forms a chemotactic gradient (By similarity). Binding of 7-alpha,25-OHC mediates the correct localization of B-cells during humoral immune responses [...] (368 aa)    
Predicted Functional Partners:
arrb1
Arrestin, beta 1.
      
 0.779
gpr37b
G protein-coupled receptor 37b.
      
 0.650
ankdd1a
Ankyrin repeat and death domain-containing 1A.
      
 0.582
Kndc1
Uncharacterized protein.
      
 0.568
Q1L949_DANRE
Si:ch211-250g4.3.
      
 0.564
RASSF4
Ras association domain family member 4.
   
  
 0.563
gpr18
G protein-coupled receptor 18.
   
 
0.561
TMEM151A
Transmembrane protein 151A.
      
 0.552
LOC101882069
Transmembrane protein 151A.
      
 0.552
sowahd
Sosondowah ankyrin repeat domain family d.
      
 0.550
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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