Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cand2Cullin-associated and neddylation-dissociated 2 (putative). (1231 aa)    
Predicted Functional Partners:
neurl1aa
Neuralized E3 ubiquitin protein ligase 1Aa.
      
 0.922
cul1b
Cullin 1b; Belongs to the cullin family.
   
 
 0.856
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 
 0.853
cul1a
Cullin 1a; Belongs to the cullin family.
   
 
 0.844
cul2
Cullin 2; Belongs to the cullin family.
    
 
 0.840
cul3a
Cullin 3a; Belongs to the cullin family.
   
 
 0.796
cul3b
Cullin 3b; Belongs to the cullin family.
   
 
 0.796
cul5a
Cullin 5a; Belongs to the cullin family.
   
 
 0.777
cul5b
Cullin 5b; Belongs to the cullin family.
   
 
 0.777
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
    
 
 0.766
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
Server load: low (16%) [HD]