STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cdc14aaCell division cycle 14Aa. (592 aa)    
Predicted Functional Partners:
cdc14b
Cell division cycle 14B.
  
  
0.904
cdc14ab
Dual specificity protein phosphatase CDC14AB; Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis.
  
  
 
0.901
fzr1a
Fizzy/cell division cycle 20 related 1 (Drosophila).
   
 0.843
fzr1b
Fizzy/cell division cycle 20-related 1b.
   
 0.830
dhrs13a.1
Dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.751
sypl2b
Novel protein containing a membrane-associating domain (Wu:fc22a07).
      
 0.743
cdc16
Cell division cycle 16 homolog (S. cerevisiae).
    
 0.743
kpnb3
Karyopherin (importin) beta 3.
   
 
 0.736
cdc23
CDC23 (Cell division cycle 23, yeast, homolog).
     
 0.736
anapc1
Anaphase-promoting complex subunit 1.
    
 0.732
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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